Massive immune haemolysis after allogeneic peripheral blood stem cell transplantation with minor ABO incompatibility
نویسندگان
چکیده
منابع مشابه
Delayed massive immune hemolysis mediated by minor ABO incompatibility after allogeneic peripheral blood progenitor cell transplantation.
BACKGROUND Bone marrow transplantation with minor ABO incompatibility may be followed by moderate delayed hemolysis of the recipient's red cells by donor-derived ABO antibodies. This reaction may be more severe after transplantation of peripheral blood progenitor cells (PBPCs). CASE REPORT A 16-year-old boy underwent an allogeneic PBPC transplant from his HLA-mismatched mother as treatment fo...
متن کاملThe Role of ABO Incompatibility in Allogeneic Peripheral Blood Stem Cell Transplant.
ABO incompatibility is not a contraindication for allogeneic bone marrow transplantation, but this procedure requires an extra effort for erythrocyte or plasma depletion in certain well established conditions. Some acute or delayed immunohematological complications such as acute or chronic hemolysis and pure red cell aplasia may be encountered. In this study the outcome and transplant related c...
متن کاملABO-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation.
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative option for a variety of malignant and non-malignant hematological and congenital diseases. Due to the fact that the human leukocyte antigen system is inherited independently of the blood group system, approximately 40-50% of all HSCTs are performed across the ABO blood group barrier. The expected immune-hematological conseq...
متن کاملImmune reconstitution after allogeneic marrow transplantation compared with blood stem cell transplantation.
Allogeneic peripheral blood stem cell grafts contain about 10 times more T and B cells than marrow grafts. Because these cells may survive in transplant recipients for a long time, recipients of blood stem cells may be less immunocompromised than recipients of marrow. Immune reconstitution was studied in 115 patients randomly assigned to receive either allogeneic marrow or filgrastim-mobilized ...
متن کاملAllogeneic peripheral blood stem cell transplantation in aplastic anemia.
Klebsiella on one occasion. Staphylococcus aureus was grown from central line tip on two occasions. He was started on meropenem and teicoplanin for 3 weeks, when he developed maxillary sinusitis, for which he was started on amphotericin B. He continued to have intermittent fever. He was also given granulocyte infusions for one week. Blood culture was sterile after 3 weeks when a Hickman cathete...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2001
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.2001.02587.x